Alikeh.
Verified Customer
I’ve struggled with cystic acne for years and tried everything - the $200 products, monthly facials, peels, etc and NOTHING worked. Then I bought this product with the hydraglow moisturizer and everything is so clear. Current cysts disappeared over a week. No new cysts. This whole brand is wonderful… and this product works wonders. Also I love the new packaging - the product stays fresher for longer
Active Breakout Routine
Active Breakout Routine
Regular price
$144.00
Regular price
$144.00
Sale price
$184.00
Unit price
per
Inside Out Clear Skin Support
This internal + external routine from The Acne Guru® tackles breakouts from multiple angles, fast.
BUNDLE & SAVE
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WELCOME TO CLEARSTEM!
Internal + External
Clear Skin Solutions
Rated “Excellent” on 50000 reviews
Because Clear Skin Changes Everything
Clinical Results
100%
felt smoother skin in 4 weeks[1]
100%
saw immediate hydration[2]
96%
saw a healthier complexion[1]
92%
saw clearer skin[1]
**Based on a 24-week clinical efficacy study where 30 participants with moderate to severe acne were given a CLEARSTEM skin routine + MINDBODYSKIN.
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
Drug Free
Gluten Free
Dairy Free
Clinically Tested
Suitable for Women + Men
Starts working in 7-10 Days*
WHY YOU'LL LOVE IT
WHY YOU'LL LOVE IT
Meet your new dream team for hormonal breakouts.
Designed to get to the root of hormonal acne without redness, peeling, or dryness, these three products work together to keep your skin happy from the inside out!
→ MINDBODYSKIN® Hormonal Acne Supplement reduces acne and improves skin clarity from the inside out.
→ CLEARITY® "The Blackhead Dissolver" serum actively works to dissolve blemishes at their source.
→ HYDRAGLOW Plant Stem Cell Moisturizer ensures optimal hydration, leaving your complexion refreshed and balanced!
These three products together strengthen your skin barrier, support healthy oil production, and deeply hydrate your complexion for a smoother, brighter glow. Use this routine to target the internal and external causes of breakouts!
Many people start seeing results in 7-10 days! Don't forget to share your before and afters.
HOW TO USE IT
This internal + external routine tackles breakouts from multiple angles.
Internal:Take 1-3 capsules of MINDBODYSKIN®* daily with food.
External:Use CLEARITY® after cleansing and before other steps. Let it absorb for 10+ minutes to let the acid get to work in your pores! No need to rinse off, simply follow with the next step in your routine.
In your AM + PM routines, apply HYDRAGLOW after serums to deeply nourish and plump skin.
Pro tips:
→ To start, use CLEARITY® every other night, then gradually increase to daily use when your skin is ready! Avoid the direct eye area.
→ CLEARITY® may increase sun sensitivity in some people. Make sure to use a quality sunscreen like YOUARESUNSHINE.
*Caution: Not pregnancy or breast-feeding safe. Do not exceed the recommended dose unless doing regular bloodwork. Consult your healthcare provider if you're managing a medical condition.
Active Ingredients:
Vitamin A (as Retinyl Palmitate), Pantothenic Acid (Vitamin B5) (as d-calcium Pantothenate), 5-HTP (5-Hydroxytryptophan), DIM (3,3’-Diindolylmethane), Milk Thistle, Dandelion (Taraxacum officinale) Extract, L-Glutathione, Turmeric (Curcuma longa) Root Extract, Protease, Betaine Hydrochloride.
Inactive Ingredients:
Silicon Dioxide (Silica), Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate.
Water/Aqua/Eau, Aloe Barbadensis (Aloe Vera) Leaf Extract*, Sodium Hyaluronate, Mandelic Acid, Propanediol, Glycerin, Hamamalis Virginiana (Witch Hazel)*, Arginine, Glycolic Acid, Gluconolactone, Xanthan Gum, Lecithin, Sclerotium Gum, Pullulan, Hydroxyacetophenone, Tetrasodium Glutamate Diacetate, Sodium Lactate, Citric Acid, Sodium PCA, Malic Acid, Glycolic Acid, Lactic Acid, Pyruvic Acid, Tartaric Acid, Citrus Nobilis (Mandarin Orange) Peel Oil, Arnica Montana Flower Extract, Camellia Sinensis Leaf Extract, Magnesium PCA, Copper PCA, Zinc PCA, Citrus Reticulata (Tangerine) Peel Oil, Glucosyl Hesperidin, Curcuma Longa (Turmeric) Root Extract, Sodium, Ubiquinone, Phenethyl Alcohol, Pentylene Glycol, Ethyl 2-Methylbutyrate, Citrus Sinensis (Orange) Peel Oil, Allyl Caproate, Raspberry Ketone, Maltol, Heliotropine, Vanillin, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Reticulata (Tangerine) Peel Oil, Triethyl Citrate.
*Certified Organic
Water/Aqua/Eau, Aloe Barbadensis Leaf Juice*, Glycerin, Propanediol, Squalane, Sodium Acrylates Copolymer, Lactobacillus Ferment, Lecithin, Pentylene Glycol, Rosa Canina Seed Oil, Potassium Sorbate, Vaccinium Myrtillus (Blueberry) Seed Oil, Raphanus Sativus (Radish) Seed Extract, Bakuchiol, Sodium Hyaluronate, Punica Granatum (Pomegranate) Seed Oil, Limonene, Isomalt, Helianthus Annuus (Sunflower) Seed Oil, Thioctic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Xanthan Gum, Boswellia Carterii Oil, Pullulan, Citrus Limon (Lemon) Peel Oil, Sclerotium Gum, Linalool, Aspartic Acid, Citrus Reticulata (Tangerine) Peel Extract, Phenylalanine, Lavandula Angustifolia (Lavender) Flower Extract, Citrus Paradisi (Grapefruit) Seed Extract, Citrus Paradisi (Grapefruit) Fruit Extract, Glutamic Acid, Sodium Hydroxide, Eugenol, Cinnamal, Citric Acid, Citral, Silica, Lactic Acid, Arginine, L-Proline, Glycine, Serine, Isoleucine, Histidine, Hippophae Rhamnoides (Sea Buckthorn) Fruit Oil*, Anthemis Nobilis Flower Extract, Threonine, Tyrosine, Lysine, Argania Spinosa Callus Culture Extract, Valine, Phenoxyethanol**, Alanine, Leucine, Sodium Benzoate, Phenethyl Alcohol, Hexanal, Ethyl Isovalerate, Benzaldehyde, cis-3-Hexenyl Acetate, Isoamyl Isovalerate, Maltol, Anisaldehyde, Methyl Anthranilate, Vanillin, Alpha-Damascone, Gamma Decalactone, Triethyl Citrate, Citrus Aurantium Dulcis (Orange) Peel Oil, Dimethylhydroxy Furanone, Ocimum Basilicum (Basil) Oil.
KEY INGREDIENTS
-
Bioavailable Vitamin A
Clinically-validated vitamin for acne that serves as a healthy alternative to harsh RX*
-
DIM
Plant-derived compound that helps fight acne at its root by targeting hormonal fluctuations.*
-
Plant Stem Cells
Generative cells that help plump skin, diminish fine lines, and improve skin texture.
-
Mandelic Acid
Holy grail of acids to exfoliate skin without irritation.
-
Squalane
Natural lipid that hydrates and protects the skin barrier by mimicking the skin's natural oils.
-
Dandelion Root
Herb that supports the body's natural detoxifying liver function.
-
Bakuchiol
Plant-based retinol alternative that boosts collagen production without causing skin sensitivity.
-
5-HTP
Naturally-occurring amino acid that helps balance the body's response to daily stress*
-
Vitamin B5
Vitamin that deeply hydrates and supports skinbarrier repair for smoother skin.
-
Pyruvic Acid
Exfoliating acid that removes dead skin cells and improves skin texture.
-
Turmeric
Plant extract known for its astringent-like properties, helping pores appear tighter.
-
Glutathione
Master antioxidant that helps brighten skin tone and improve post-acne dark spots*
GOOD FOR
Clarifying, Breakout Prevention
FEATURING
MINDBODYSKIN®, CLEARITY®, HYDRAGLOW
WHEN TO USE IT
Daily
KEY INGREDIENTS
Bioavailable Vitamin A, Mandelic Acid, Plant Stem Cells
Our Standards
No Pore-Clogging Ingredients, Ever
No Pore Cloggers
100% free from breakout-causing pore cloggers
Clinically Tested
Third party validated safety and results
Internal + External
Supporting your clearest skin from all angles
Sensitive Skin Friend
lyAlways gentle, soothing, and barrier-friendly
Clear Pore Promise™
Clear Pore Promise™
Our topicals contain no pore-clogging ingredients, ever, and our supplements use whole-body ingredients to support clear skin from the inside out.
WE NEVER USE
Parabens
PEGs (Polyethylene Glycols)
Petrochemicals (e.g., mineral oil, petrolatum, paraffin wax)
Phenoxyethanol (over 1%)
Phthalates
Sodium Lauryl Sulfate (SLS) and Sodium Laureth Sulfate (SLES)
Synthetic Dyes and Fragrances
TBHQ (Tertiary Butylhydroquinone)
Oxybenzone
Toluene
Triclosan
--------------------------------------------------------
Pore-Clogging Ingredients
Benzoyl Peroxide
Aluminum Chlorohydrate
BHA (Butylated hydroxyanisole)
BHT (Butylated hydroxytoluene)
Coal Tar
EDTA (Ethylene Diamine
Tetraacetic Acid)
Formaldehyde and Formaldehyde-Releasing Preservatives
Nanoparticles
Join the #CLEARSTEMFAM
-
Jessica Clarke Higgins
Licensed medical esthetician, Acne Specialist + Founder Just Skin Den - Denver, CO
-
Emily Morrow
Certified Nutritional Therapy Integrative Health Practitioner + serves as CLEARSTEM Skincare's Acne Lab Specialist
-
Alyssa Lynch
Multifaceted actress and model - Los Angeles, CA
In the Press
We're turning heads in the skincare world. From buzz-worthy product features to expert tips, check out how we're shaking things up and making headlines.
Our Story
Meet the acne brand that bridges internal and external skincare through supplements and topicals with no-pore clogging ingredients, ever.
It all started with two women determined to take their acne into their own hands.
Danielle struggled with severe acne—and many failed treatment attempts—for years before clearing up her skin by extensively researching the causes of acne and becoming a Licensed Clinical Esthetician.
In 2014, she founded The San Diego Acne Clinic, where she earned the title of The Acne Guru® due to her astonishing 98% success rate in clearing her patients’ skin across all ages, ethnicities, and skin types.
Among her success stories is Kayleigh Christina, an Integrative Health Practitioner + Nutritionist who couldn’t clear her cystic acne until visiting Danielle at her clinic and adopting her approach.
Their shared passion for wellness and transformation inspired them to create CLEARSTEM together to help more people achieve the skin they could previously only dream of.
CLEARSTEM is a labor of love, here to empower you with internal + external solutions for your skin. We’re so glad you’re here!
Meet Danielle Gronich
Danielle "The Acne Guru®" Gronich is the co-founder, chief formulator and CEO of CLEARSTEM.
After over 10 years of personal struggle with chronic cystic acne and numerous unsuccessful treatments—including Accutane, antibiotics, birth control, and laser treatments—Danielle dove into clinical research and returned to school to find answers.
In 2014, she opened the San Diego Acne Clinic, where her comprehensive methods achieved a 98% success rate in clearing clients' skin. In 2016, she founded CLEARSTEM to make her methods accessible to all the people who need it.
Meet Kayleigh Christina
Kayleigh Christina is an Integrative Health Nutritionist, co-founder, and Chief Marketing Officer (CMO) of CLEARSTEM.
Kayleigh's journey began with multiple health issues and struggling with cystic acne in her mid-twenties. After finding no success with various doctors and dermatologists, she discovered San Diego Acne Clinic and met Danielle Gronich. Under Danielle's comprehensive, whole-body approach, Kayleigh achieved clear skin and a renewed commitment to root-cause solutions.
An advocate for wellness and making a positive impact on people's lives, Kayleigh is also an author, podcaster, and investor in health-centric consumer packaged goods (CPG) brands.
Frequently Asked Questions
Who should take this product?
Who should take this product?
This product is for anyone with acne or oily/acne-prone skin. This product serves the market who wants more control over their acne without having to take toxic medications like antibiotics, or for parents who do not want to put their child on something like Accutane.
How long does it take to see results?
How long does it take to see results?
Initial results can be felt after the 1st week, with full effects kicking in around weeks 3 and 4.
How many do you take and when?
How many do you take and when?
Serving size is 3 capsules with a meal (it works better with food as it has digestive enzyme and Vitamin A is fat-soluble). For smaller people who weigh less than 120 lb, they may be fine to just take 2 capsules. For those who get too relaxed from the 5-TP, we recommend taking in the evening.
What are the results to look out for when taking it?
What are the results to look out for when taking it?
Customers will not notice much for the first few days, but then may experience a better stress-response and feelings of calm and peace. After 1 week customers should notice less new acne and a reduction in size and inflammation of pre-existing acne. After 2 weeks customers should see a significant reduction in both new and existing acne, along with elevated feelings of well-being. After 1 month, customers should notice a smoother menstrual experience, better sleep, and significantly clearer skin that heals faster and is less oily throughout the day.